Vol. 33, Issue 2-3, pp. 489-503

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  2. Optica Applicata Vol. 33, Issue 2-3, pp. 489-503 (2003)
Vol. 33 Issue 2-3 pp. 489-503

Investigation of photo-physical properties of selected diaminoacid protoporphyrin derivatives (PP(AA)2Arg2). I. Determination of quantum yield of fluorescence

Shu Ye, Mariusz Czuba, Anna Romiszewska, Jerzy Karolczak, Alfreda Graczyk

Keywords

photosensitizers, photodynamic therapy, quantum yield of fluorescence

Abstract

An new generation of photosensitizers for photodynamic therapy (PDT) has been investigated. Different amino acids (Ala, Ser, Thr, Phe and Trp) were bound to protoporphyrin (PP). The quantum yield of fluorescence of porphyrin solutions was investigated. Fluorescence spectra and lifetimes of excited porphyrins were determined, too. The purpose of this work was to evaluate the quantum yield of fluorescence of different PP(AA)2Arg2 derivatives, since it is crucial for choosing proper ingredients of photosensitizer for diagnosis and therapy in PDT.

Vol. 33
Issue 2-3
pp. 489-503

1.12 MB
OPTICA APPLICATA - a quarterly of the Wrocław University of Science and Technology, Faculty of Fundamental Problems of Technology