Vol. 33, Issue 2-3, pp. 489-503 (2003)

Abstract

An new generation of photosensitizers for photodynamic therapy (PDT) has been investigated. Different amino acids (Ala, Ser, Thr, Phe and Trp) were bound to protoporphyrin (PP). The quantum yield of fluorescence of porphyrin solutions was investigated. Fluorescence spectra and lifetimes of excited porphyrins were determined, too. The purpose of this work was to evaluate the quantum yield of fluorescence of different PP(AA)₂Arg₂ derivatives, since it is crucial for choosing proper ingredients of photosensitizer for diagnosis and therapy in PDT.