Vol. 46, Issue 3, pp. 483-496 (2016)

Vol. 46 Issue 3 pp. 483-496

Influence of sodium hyaluronate on dehydration and water distribution in soft contact lenses

Daria Rajchel, Katarzyna Krysztofiak, Andrzej Szyczewski

Keywords

contact lens dehydration, sodium hyaluronate, gravimetry, differential scanning calorimetry

Abstract

The purpose of this investigation was to examine the influence of sodium hyaluronate (HA) solution on contact lens dehydration and the distribution of water in lens materials. These parameters were measured with gravimetry and differential scanning calorimetry. Five commercial soft contact lenses were used. They represented four FDA (Federal Drug Administration) groups: Air Optix Night & Day Aqua and Acuvue Oasys (I FDA group), Proclear 1-Day (II FDA group), PureVision (III FDA group) and 1-Day Acuvue Moist (IV FDA group). All materials were investigated with two preservative-free HA solutions 0.1% and 0.3%. HA solutions influenced the water content and the dehydration rate of some examined lenses. For three lenses (Oasys, Proclear, Moist) water content of HA lenses was greater than control. Significant slowdown of dehydration rate under HA during the first 20 min was observed only for Proclear. Phase I of dehydration increased significantly with HA solutions in case of Moist and Proclear. For Night & Day and Oasys phase I appeared under HA solution while it was not present for control lenses. Duration of the phase I was strongly correlated with water content of the lenses (R2 = 0.844). The amount of freezable and non-freezable water depended strongly on characteristics of lens material and its interaction with HA molecules. Proclear seems to be the most prone to attach HA molecules which affect changes in dehydration characteristics and water behavior in the polymer. PureVision might be considered as the most resistant to HA in terms of dehydration dynamics and water distribution. All measured parameters seem to be dependent more on material properties than HA concentration.

Vol. 46
Issue 3
pp. 483-496

0.43 MB

Corresponding address

Optica Applicata
Wrocław University of Science and Technology
Faculty of Fundamental Problems of Technology
Wybrzeże Wyspiańskiego 27
50-370 Wrocław, Poland

Publisher

Wrocław University of Science and Technology
Faculty of Fundamental Problems of Technology
Wybrzeże Wyspiańskiego 27
50-370 Wrocław, Poland

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